Programm für das Sommersemester 2023
Thursdays, 10:30 Uhr s.t.
K. Binder/ A. Nikoubashman / F. Schmid / G. Settanni / T. Speck / M. Sulpizi / P. Virnau
Newtonraum, 01-122, Staudingerweg 9
17.05.23 | Bernhard von Vacano, BASF | |
PW 059721 | ||
18:00 Uhr s.t., Minkowski Room, 05-119, Staudingerweg 7, | ||
https://trr146.uni-mainz.de/activities/ |
31.05.23 | Nico Bischoff, R+V | |
Hybrid event; PW: 359038 | ||
16:00 Uhr s.t., KpH lecture room, 00-200, Johann-Joachim-Becher-Weg 45 | ||
PW: 359038 |
12.06.23 | Apratim Chatterji, IISER-Pune, Pune | |
I shall present our recent results where we modify internal-topology of ring polymers (bead-spring model) to obtain localization of polymer segments within cylindrical confinement. We tried out a variety of topologies to establish the entropic principles which lead to localization of polymer segments. Two polymers in a mixed state under cylindrical confinement undergo segregation, and again topology plays an important part in determining the forces which lead to segregation and subsequent localization. We have used this understanding to predict the localization of loci (polymer segments) of bacterial DNA polymers, as the chromosome is replicating and segregating. It is known that some simple bacterial cells do not have the required machinery to separate their chromosomes within the cell. We have matched out model simulations results for two different bacterial chromosomes, moreover, our model simulation match data from two different experimental techniques ( HiC and FISH) which are complementary in spirit. I am extending our topology driven organization understanding in a variety of scenarios, some of which will be useful to understand more complex organization of chromosomes within more complex cells as well in more complex scenarios of multifork replication within the bacterial cell. | ||
14:30 Uhr s.t., Medienraum (IPH, 03-431) | ||
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21.06.23 | Abhishek Singharoy, Arizona State University | |
Molecular modeling of biomolecular assemblies exemplifies a disruptive area holding both promises and contentions. We will start with a brief story of simulating the first ever cell organelle in molecular details to find how nature has chosen survival fitness over efficiency of energy transfer as an evolutionary design (Cell, 2020). Despite such advances in exascale computing, biophysical simulation continues to grapple with handling molecular diversity. So, we will employ deep learning approaches often used in Google searches, called the inception network, to marry interaction signatures from Alphafold models and proteomics analysis with predictable patient outcomes (Cell Sys, 2022). An application will highlight how molecular modeling is used at an industrial scale to de-risk vector-based vaccines for distribution across 194 countries (Sci Adv 2021). We will conclude by seeing how transient interactions are difficult to predict, and path integrals with reinforcement learning offer a possible way to track diversity of dynamics (NeurIPS, 2022). | ||
14:30 Uhr s.t., Minkowski Room, 05-119, Staudingerweg 7 | ||
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22.06.23 | Bettina Keller, Freie Universität Berlin | |
Rare-event simulations with Girsanov reweighting | ||
14:30 Uhr s.t., Minkowski Room, 05-119, Staudingerweg 7, | ||
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07.07.23 | Erik Kalz and Abhinav Sharma, Leibniz-Institut für Polymerforschung Dresden & TU Dresden | |
The Physics of Odd Systems | ||
14:30 Uhr s.t., Minkowski Room, 05-119, Staudingerweg 9 | ||
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13.07.23 | Martin Vögele, Schrödinger | |
Hybrid meeting; ID: 814 7712 9515, Passcode: 008795 | ||
18:00 Uhr s.t., hybrid meeting, Minkowski Room, 05-119, Staudingerweg 7 | ||
Time to be determined. |
20.07.23 | Jerelle Joseph, Princeton University | |
Accurate models for interrogating and engineering biomolecular condensates | ||
14:30 Uhr s.t., Online | ||
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07.09.23 | Yuichi Masubuchi, Department of Materials Physics, Nagoya University, Japan | |
Effect of node functionality on the fracture of polymer networks | ||
13:30 Uhr s.t., Online | ||
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14.09.23 | Mike Howard, Chemical Engineering, Auburn University, USA | |
GRK 2516 Soft Matter Seminar | ||
14:30 Uhr s.t., Minkowski Room, 05-119, Staudingerweg 7 | ||
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Koordination: | Kontakt: |
K. Binder A. Nikoubashman F. Schmid G. Settanni T. Speck M. Sulpizi P. Virnau L. Stelzl | Lukas Stelzl |